Measurement of the Effect of Reflexology Applied During Early Lactation on VEGF, Endostatin, MMP and Thrombospondin Levels Using a Biosensor
DOI:
https://doi.org/10.5281/zenodo.15700692Keywords:
Reflexology, Lactation, VEGF, Endostatin, MMP and Thrombospondin, BiosensorAbstract
An important one of these is lactation, which takes place at the age of fertility. Reflexology is a printing technique applied to reflex points, in ears, hands and feet which correspond to the whole body, its’ organ and systems. Despite the large number of studies concerning reflexology, no studies have been conducted on its effects on lactation hormones. Since the postpartum reflexology provides relief for the mother and minimizes the anxiety and tension felt, we have previously looked at the effect of reflexology on oxytocin, prolactin, noradrenaline hormone levels, angiogenetics and antiangionetic factors and their effects on lactation by the Elisa method. In the study, we aimed to investigated the Sensitivity and Specificity of the biosensors produced for these markers. This study consisted of 70 cases (35 people for pituitary and reproductive organs, 35 people for lumbosacral area reflexology) and 35 controls (this group was selected from puerperant women in the same age group as the case group and no intervention was performed). VEGF, Endostatin, MMP, thrombospondin oxytocin, prolactin and noradrenaline levels were analyzed by biosensors from the blood taken from the experimental and control groups within 1-4 hours. Compared to the ELISA results, the samples taken were found to have high Sensitivity and Specificity. Biosensors are widely used in clinical diagnosis, medical applications, bioreactors, preparation of bacterial and viral diagnostic kits, drug production. We think that biosensors can be preferred for analysis because of their simple, inexpensive, easy-to-use, high Sensitivity and Specificity.
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