Leaky Gut and Leaky Calves: Umbrella Review for Evidence of Proof and Published Articles

Leaky Gut and Leaky Calves

Authors

DOI:

https://doi.org/10.5281/zenodo.17998455

Keywords:

Calf, Intestinal Permeability, Leaky Gut, Zonulin

Abstract

In the present article we, as presenting authors write an umbrella review for detailed determination of ‘leaky gut’, ‘intestinal permeability’, ‘zonulin’ and for better understanding for the readers. Tight junctions, describing foremost barrier within the paracellular route among intestinal epithelial cells. Disturbed tight junctions consequently alter intestinal hyperpermeability (namely “leaky gut”) and has been linked to the proposed pathogenesis of several different disorders also among calves and cattle. The aim was to write an umbrella review providing an overview of proof of evidence for participation of leaky gut and related zonulin levels also involving tight junction breakdown. Several studies were summarized, which could have helped better basic understanding of this disruption and its relevant mechanistic consequences. Taking into account those data, veterinary surgeons could probably lead to prevention/treatment of several different disorders by using nutritional additives, which were also briefly explained at this manuscript also.

References

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Published

2025-12-24

How to Cite

Ural, K., Erdoğan, H., Paşa, S., Erdoğan, S., & Özalp, T. (2025). Leaky Gut and Leaky Calves: Umbrella Review for Evidence of Proof and Published Articles : Leaky Gut and Leaky Calves. Kafkasya Journal of Health Sciences, 2(2), 54–57. https://doi.org/10.5281/zenodo.17998455

Issue

Vol. 2 No. 2 (2025): Kafkasya Journal of Health Sciences

Section

Articles

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Copyright (c) 2025 Kerem Ural, Hasan Erdoğan, Serdar Paşa, Songül Erdoğan, Tahir Özalp

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